Two women in their 30s die after receiving fillers during cosmetic surgery in South Korea

The case of two South Korean women in their 30s who died after receiving Y-zone filler injections during cosmetic surgery has been made public in a domestic academic journal.
In February of this year, medical staff from Seoul National University's Department of Forensic Medicine and the National Institute of Scientific Affairs
A paper published in the Korean Journal of Legal Medicine detailed the autopsy cases of Ms. A, a 38-year-old woman, and Ms. B, a 35-year-old woman, who died after receiving Y-zone filler injections.
First, Ms. A had a Y-zone filler treatment at a gynecology and obstetrics clinic, and on her way home she suddenly lost consciousness and collapsed, and was admitted to an emergency hospital.
He reportedly experienced palpitations and dizziness. Over the course of seven months, Mr. A had been injected with a total of 47 milliliters of filler in the same area over four separate occasions. Mr. A was taken to the emergency room and began to experience difficulty breathing.
She then showed movements similar to those of a seizure, and was intubated and transferred to the intensive care unit. She was then administered vasoconstrictors and cardiac stimulants, but her heart function gradually declined, and she died 10 days after being admitted to the hospital.
The autopsy revealed that Ms. A had a large blood clot in her vagina and had been injected with a large amount of filler. It was also confirmed that her lungs were in a state of congestion, with blood volume increasing and blood not circulating properly.
The medical team explained that the filler had spread to the surrounding blood vessels and blocked them. Ms. B, a 35-year-old woman who had received filler treatment in the same Y-zone as Mr. A, suffered a heart attack four minutes after the treatment.
Mr. B underwent filler treatment while under anesthesia with ketamine, midazolam, and propofol. He was then treated in the intensive care unit for a month, but died of hypoxic brain damage and pneumonia.
She eventually died. When the autopsy examiner examined her vagina, he found that some blood vessels in the submucosa and elsewhere had been embolized by filler, a non-thrombotic pulmonary embolism.
A substance that is rarely found in normal blood vessels has clogged the blood vessels through the pulmonary circulation. The medical team said, "It is rare, but the filler may have been injected directly into the vein or may have migrated into the vein due to high local pressure.
"There have been multiple reported cases of non-thrombotic pulmonary embolism following Y-zone filler injection, and more than half of the patients died," he said.
He added, "Y-zone filler has a significant risk of vascular complications after injection, so clinicians must be aware of these risks and refrain from performing the procedure."